Thermo Fisher Scientific Staff Process R&D Scientist in Florence, South Carolina
Job Title: Staff Process R&D Scientist
Requisition ID: 145838BR
When you're part of the team at Thermo Fisher Scientific, you'll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you'll be supported in achieving your career goals.
Location/Division Specific Information:
6173 East Old Marion Highway, Florence South Carolina
How will you make an impact?
Investigate, create & validate new scientific methodologies used to manufacture and control raw materials, production intermediates, and final products on highly unique and complex projects. May be involved in pre-clinical, clinical, and/or post-marketing stages of drug development. Works on significant technical/scientific project activities to execute strategies and technical solutions that meet client needs and expectations through broad expertise. Participates in technical discussions with clients with a high level of technical proficiency. Engages in creation of processes and equipment design for clinical, scale up, registration and/or commercial production batches, including technology transfer of projects to and from clients. Evaluates and contributes to the design of manufacturing processes and supports problem solving as necessary with leadership and independent judgement. Makes decisions that frequently require developing new options to solve complex problems.
What will you do?
Develop feasible chemical processes to synthesize drug intermediates and APIs that meet or exceed the quality requirements from clients.
Collect reliable process data through designed laboratory experiments with accurate, detailed documentation for process evaluation, development and troubleshooting.
Record and analyze scientific data/observations in detail. Summarize and interpret process data to draw logical conclusions. Write technical updates/reports. Participate in technical discussions with internal teams and clients.
Proficient analytical knowledge for compound identification and structure elucidation is required including at least NMR, IR, HPLC, GC, and MS.
Develop new processes that meet or exceed the expectations from clients and provide innovation as necessary.
Prepare detailed process development report to support manufacturing and regulatory requirements.
Draft, review Operating Instructions, Deviations, Change Controls, and Investigative documentation.
Execute Operating Instructions for laboratory scale production under SOP/cGMP guidelines.
Evaluate technical package and successfully lead process technology transfer.
Provide timely technical support for scale-up production, quality and other inter-departmental needs.
Lead projects with minimal supervision; may lead projects, including but not limited to managing process development timelines and deliverables, coordinating process development activities.
Fit in a multidisciplinary team with flexibility to carry out fast- turnaround projects.
Research industry practices and processes and apply to innovative development internally and for client products.
Lead projects with minimal supervision. Manage project timelines and deliverables.
How will you get here?
- PhD in Chemistry or commensurate experience required - Organic Chemistry PhD preferred
2-5 years of scientific experience in a related field. Experience working in Pharmaceutical Industry preferred.
Project management experience strongly preferred.
Process Validation experience preferred.
Knowledge, Skills, Abilities:
Good knowledge and understanding of chemistry and analytical instrumental technologies. Good knowledge of qualitative and quantitative chemical or microbiological analysis. Good knowledge of quality and regulatory requirements in the pharmaceutical industry, including pharmaceutical GMPs and descriptive organic chemistry. Good problem solving skills and logical approach to solving scientific problems. Proficiency with HPLC, GC, LC/MS and Dissolution techniques. Good interpersonal and communication skills (both oral and written). Good presentation skills to present information to customers, clients, and other employees. Ability to read, analyze, and interpret technical procedures and governmental regulations. Ability to write standard operating procedures, simple protocols, and reports. Ability to respond to common inquiries or complaints from customers or regulatory agencies. Ability to apply mathematical operations, to such tasks as determination of test reliability, analysis of variance and correlation techniques.
Position requires ordinary ambulatory skills and physical coordination sufficient to move about office locations; ability to stand, walk, stoop, kneel, crouch periodically for prolonged periods of time; manipulation (lift, carry, move) of light to medium weights of 10-35 pound pounds; arm, hand and finger dexterity, including ability to grasp and type for prolonged periods of time; visual acuity to use a keyboard, computer monitor, operate equipment, and read materials for prolonged periods of time; ability to sit, reach with hands and arms, talk, and hear for prolonged periods of time. Safety glasses, safety shoes, lab coat, latex or similar gloves, safety apron, organic respirator occasionally.
Disclaimer Statement: 'The above statements are intended to describe the general nature and level of work being performed by people assigned to this job. They are not intended to be an exhaustive list of all responsibilities, duties, and skills required of personnel so classified.'
At Thermo Fisher Scientific, each one of our 70,000 extraordinary minds has a unique story to tell. Join us and contribute to our singular mission-enabling our customers to make the world healthier, cleaner and safer.
Apply today! http://jobs.thermofisher.com
Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.
Thermo Fisher Scientific is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, creed, religion, color, national or ethnic origin, citizenship, sex, sexual orientation, gender identity and expression, genetic information, veteran status, age or disability status.